Fragment-Based Lead Discovery (FBLD)

FBLD-1The department is coordinating several Marie Skłodowska-Curie Innovative Training Networks (ITN) that advance particular exciting areas of research that are of importance to the European Union. These projects involve the key European partners in a certain research field. One example is the ITN called FRAGNET (www.fragnet.eu) that has been set up to develop new approaches and technologies for Fragment-Based Lead Discovery (FBLD). This design-intensive approach aims to very efficiently discover and develop molecules with promising biological activities. The CPS department (PI Prof. Iwan de Esch) coordinates the consortium that trains a new generation of 15 young researchers in the much needed holistic understanding of all aspects of FBLD. Work packages include fragment libraries generation, experimental FBLD screening technologies, computational approaches and FBLD applications in protein target modulation and drug development. 

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