Structural Biology

IMC logoOur research focuses on the dynamics of intra- and intermolecular interactions of proteins. It aims on the visualization of structural alterations in the course of enzymatic activity, transmembrane transport and regulation in vitro and in vivo.

The department is currently organized in four teams or subgroups, three of which are engaged in their own particular research topic:

  • 14-3-3 proteins are involved in high level regulatory processes in plant and animal cells. These proteins are the topic of the group of Dr. B. de Boer.
  • F0F1 ATP synthase is one of few rotational biomolecular motors known today. The enzyme stands central in energy metabolism of almost every living cell. A group headed by Dr. D. Bald works on this protein complex.
  • The Twin Arginine Transport (Tat) system has the unique capability to transport folded or even multimeric proteins across biological membranes. A group headed by Dr. Y. Bollen examines several aspects of this transport process.

Structural Biology website